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Imunotherapy in combination with chemotherapy is emerging as a new standard of care in this setting, and the approval of Imfinzi offers an important new option for patients with mismatch repair deficient disease, Dave Fredrickson, executive vice president of the oncology business unit at AstraZeneca, said in a press release

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(2021) 160:20618 e13

doi: 10.1002/jlb.54.5.444 154 BorrielloFIannoneRDi SommaSLoffredoSScamardellaEGaldieroMRet al

This process can at least increase phagocytosis of red blood cells and lead to reduced iron toxicity and inflammatory responses